Sorry, that's my mistake. I got that config file confused with the nrpe.cfg.
The nrdp.conf file is already located in /etc/apache2/sites-enabled/
root@myserver:/etc/apache2/sites-enabled# ls -lah
total 20K
drwxr-xr-x 2 root root 4.0K Oct 2 21:40 .
drwxr-xr-x 8 root root 4.0K Sep 29 22:01 ..
lrwxrwxrwx 1 root root 35 Apr 6 17:19 000-default.conf -> ../sites-available/000-default.conf
-rw-r--r-- 1 root root 3.0K Sep 11 23:25 nagios.conf
-rw-r--r-- 1 root root 1.6K Sep 11 23:25 nagiosql.conf
-rw-r--r-- 1 root root 180 Sep 29 18:11 nrdp.conf
root@myserver:/etc/apache2/sites-enabled# cat nrdp.conf
<Directory "/usr/local/nrdp">
Options None
AllowOverride None
Order allow,deny
Allow from all
Require all granted
</Directory>
Alias /nrdp "/usr/local/nrdp/server"
root@myserver:/usr/local/nrdp# ls -lah
total 24K
drwxr-xr-x 4 nagios nagios 4.0K Sep 28 00:41 .
drwxr-xr-x 12 root root 4.0K Sep 28 00:41 ..
-rw-r--r-- 1 nagios nagios 1.5K Sep 28 00:41 CHANGES.rst
drwxr-xr-x 2 nagios nagios 4.0K Sep 28 01:12 clients
-rw-r--r-- 1 nagios nagios 4.0K Sep 28 00:41 LICENSE.rst
drwxr-xr-x 4 nagios nagios 4.0K Sep 28 02:13 server
root@myserver:/usr/local/nrdp# cat /etc/group | grep nag
www-data

33:nagios,www-data
nagios

1001:nagios,www-data
nagcmd

1002:nagios,www-data